Enkephalin (PENK) Mouse Monoclonal Antibody [Clone ID: 1194/334]

CAT#: AM01180PU-N

Enkephalin (PENK) mouse monoclonal antibody, clone 1194/334, Purified

Specifications

Product Data

• Clone Name: 1194/334
• Applications: ELISA
• Recommended Dilution: ELISA.
• Reactivities: Mammalian
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Native.
• Specificity: This antibody reacts to MET-Enkephalin. Cross reactivities with other enkephalins to be determined.
• Formulation: PBS, pH 7.2 containing 10 mM Sodium Azide
  State: Purified
  State: Liquid purified Ig
• Concentration: lot specific
• Purification: Protein A chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens proenkephalin (PENK)
• Database Link:
  Entrez Gene 5179 Human
• Background: Met-enkephalin (tyr-gly-gly-phe-met) and leu-enkephalin (tyr-gly-gly-phe-leu) are pentapeptides which compete with and mimic the effects of opiate drugs. Although interest in enkephalins stems largely from their possible role in the brain, the richest source of these peptides is the adrenal gland. The amino acid sequence shows that the precursor is 267 amino acids long and contains 6 interspersed Met-enkephalin sequences and 1 Leu-enkephalin sequence. The precursor does not contain the sequences of dynorphin, alpha-neo-endorphin or beta-endorphin. (Because of structural similarities it had been postulated that beta-endorphin is precursor of Met-enkephalin, and that dynorphin or alpha-neo-endorphin is precursor of Leu-enkephalin.)
• Synonyms: preproenkephalin; proenkephalin

Reference Data

• Protein Families: Secreted Protein