TPSAB1 Mouse Monoclonal Antibody [Clone ID: G3]

CAT#: AM10146SU-N

TPSAB1 mouse monoclonal antibody, clone G3, Supernatant

Product Images

Formalin-Fixed, Paraffin-Embedded Human neurofibroma stained with Tryptase antibody Cat.-No. AM10146SU-N using peroxidase conjugate and DAB chromogen. Note the cytoplasmic staining of mast cells.

Specifications

Product Data

• Clone Name: G3
• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Sections: 1/50-1/200
  Pretreatment of deperaffinized tissue with heat-induced epitope retrieval is recommended.
  Use Polymer anti Mouse/Rabbit IgG as a detection system.
  Positive Control: Mast cells containing tissue or tumors.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Purified Human Tryptase protein.
• Specificity: This antibody recognizes Tryptase.
  Cellular Localization: Cytoplasmic.
• Formulation: State: Supernatant
  State: Liquid Tissue Culture Supernatant with 0.2% BSA and 15mM Sodium Azide.
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens PMS1 homolog 2, mismatch repair system component (PMS2), transcript variant 1
• Database Link:
  Entrez Gene 5395 HumanEntrez Gene 7177 Human
• Background: Tryptases constitute a subfamily of trypsin-like proteinases, stored in the mast cell secretory granules and basophils. Upon cellular activation, these enzymes are released into the extracellular environment.
  Anti-tryptase is a good marker for mast cells, basophils, and their derivatives.
• Synonyms: TPSB1, Tryptase I, Mast Cell Tryptase

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Mismatch repair