Aurora A (AURKA) (full length) Mouse Monoclonal Antibody [Clone ID: 7A3]

CAT#: AM20483PU-N

Aurora A (AURKA) (full length) mouse monoclonal antibody, clone 7A3, Aff - Purified

Product Images

Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Panel A: Hela cells stained with anti-Aurora A (clone 7A3) and FITC-conjugate Goat anti-Mouse antibody. Panel B: Hela cells stained with DAPI to indicate nuclei.

Specifications

Product Data

• Clone Name: 7A3
• Applications: IF, IHC, WB
• Recommended Dilution: Immunofluorescence.
  Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgM
• Clonality: Monoclonal
• Immunogen: Full length recombinant Aurora A protein
• Specificity: This antibody recognizes Aurora-Related Kinase 1 (ARK1/AURKA).
• Formulation: PBS, pH 7.4 containing 0.09% Sodium Azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens aurora kinase A (AURKA), transcript variant 2
• Database Link:
  Entrez Gene 6790 Human
• Background: Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment.
• Synonyms: AURKA, AIK1, ARK1, AURA, BTAK, STK15, STK6, Aurora/IPL1-related kinase 1, AURORA2

Reference Data

• Protein Families: Druggable Genome, Protein Kinase, Stem cell - Pluripotency
• Protein Pathways: Oocyte meiosis