GMP Synthase (GMPS) Mouse Monoclonal Antibody [Clone ID: 1D10]

CAT#: AM20966PU-N

GMP Synthase (GMPS) mouse monoclonal antibody, clone 1D10

Product Images

Detection limit for recombinant GST tagged GMPS is approximately 0.1 ng/ml as a capture antibody.

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  Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 1D10
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant protein, GMPS (NP_003866, 108 a.a. ~ 216 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Specificity: This antibody reacts to Gmp Synthase (GMPS).
• Formulation: PBS, pH 7.2
  State: Liquid purified Ig fraction
• Concentration: 0.48 mg/ml
• Purification: Protein A Chromatography
• Gene Name: Homo sapiens guanine monophosphate synthase (GMPS)
• Database Link:
  Entrez Gene 8833 Human
• Background: In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.
• Synonyms: Glutamine amidotransferase

Reference Data

• Protein Families: Stem cell - Pluripotency
• Protein Pathways: Drug metabolism - other enzymes, Metabolic pathways, Purine metabolism