YAP1 Mouse Monoclonal Antibody [Clone ID: 2H1]

CAT#: AM20983PU-N

YAP1 mouse monoclonal antibody, clone 2H1

Product Images

YAP1 monoclonal antibody, clone 2H1 Western Blot analysis of YAP1 expression in Hela NE.

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  Detection limit for recombinant GST tagged YAP1 is approximately 0.03 ng/ml as a capture antibody.

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  Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Colon, muscularis mucosa: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Uterus: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Immunofluorescence of monoclonal antibody to YAP1 on HeLa cell (antibody concentration 40 ug/ml).

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Specifications

Product Data

• Clone Name: 2H1
• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA.
  Immunofluorescence: 40 µg/ml.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: Recombinant protein, YAP1 (NP_006097, 53 a.a. ~ 162 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Specificity: This antibody recognizes Yes-Associated Protein, 65 KDa (YAP1).
• Formulation: PBS, pH 7.2
  State: Liquid purfied Ig fraction
• Concentration: 0.5 mg/ml
• Purification: Protein A Chromatography
• Gene Name: Homo sapiens Yes associated protein 1 (YAP1), transcript variant 1
• Database Link:
  Entrez Gene 10413 Human
• Background: Transcriptional regulator which can act both as a coactivator and a corepressor and is the critical downstream regulatory target in the Hippo signaling pathway that plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis.
• Synonyms: YAP, YAP65

Reference Data

• Protein Families: Druggable Genome