HEPC (HAMP) (25-85) Mouse Monoclonal Antibody [Clone ID: 1F9]

CAT#: AM21007PU-N

HEPC (HAMP) (25-85) mouse monoclonal antibody, clone 1F9

Product Images

Detection limit for recombinant GST tagged HAMP is approximately 0.03 ng/ml as a capture antibody.

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  Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 1F9
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: HAMP (AAH20612, 25 a.a. ~ 85 a.a) full length recombinant protein with GST tag.
• Specificity: This antibody recognizes Hepcidin Antimicrobial Peptide (HAMP) aa 25-85.
• Formulation: PBS, pH 7.4
  State: Liquid purified Ig fraction
• Concentration: 0.5 mg/ml
• Purification: Protein A Chromatography
• Gene Name: Homo sapiens hepcidin antimicrobial peptide (HAMP)
• Database Link:
  Entrez Gene 57817 Human
• Background: Hepcidin, an human antimicrobial peptide, contains a leader sequence, a proteolysis site and a C-terminal 25 amino acid active peptide. This peptide is most active against gram-positive bacteria, but also inhibits the growth of certain yeast and gram-negative bacteria. HAMP also functions as a signaling molecule involved in the maintenance of iron homeostasis. In conjugation with HFE it seems to regulate both intestinal iron absorption and iron storage in macrophages. Mutations in HAMP are found in juvenile hemochromatosis.
• Synonyms: LEAP-1, HEPC, LEAP1, PLTR

Reference Data

• Protein Families: Secreted Protein, Transmembrane