Junctional Adhesion Molecule 2 (JAM2) (29-299) Mouse Monoclonal Antibody [Clone ID: 1G4]

CAT#: AM31113PU-N

Junctional Adhesion Molecule 2 (JAM2) (29-299) mouse monoclonal antibody, clone 1G4, Purified

Product Images

Western Blot analysis of JAM2 expression in LNCaP cells with JAM2 monoclonal antibody, clone 1G4.

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  Detection limit for recombinant GST tagged JAM2 is approximately 0.1ng/ml as a capture antibody.

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  Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 1G4
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: JAM2 (AAH17779, 29 a.a. ~ 299 a.a) full length recombinant protein with GST tag
• Specificity: This antibody reacts to JAM2 / JAMB at aa 29-299.
• Formulation: PBS, pH 7.4
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: 0.48 mg/ml
• Purification: Affinity chromatography on Protein A
• Gene Name: Homo sapiens junctional adhesion molecule 2 (JAM2), transcript variant 1
• Database Link:
  Entrez Gene 58494 Human
• Background: JAM2 belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene.
• Synonyms: JAM-B, C21orf43, VEJAM

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Epithelial cell signaling in Helicobacter pylori infection, Leukocyte transendothelial migration, Tight junction