GNLY Mouse Monoclonal Antibody [Clone ID: B-R32]
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Specifications
Product Data | |
Clone Name | B-R32 |
Reactivities | Human |
Host | Mouse |
Isotype | IgG2b |
Clonality | Monoclonal |
Immunogen | Recombinant Human Granulysin (NKG5 and LAG-2) |
Specificity | This antibody recognizes both natural and recombinant Granulysin. |
Formulation | Phosphate-buffered saline. Sterile filtered through 0.22 µm and treated to remove endotoxins. Carrier and preservative free. State: Azide Free State: Liquid purified Ig fraction |
Concentration | 1.0 mg/ml |
Purification | Ion Exchange Chromatography |
Gene Name | Homo sapiens granulysin (GNLY), transcript variant 2 |
Database Link | |
Background | The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified. |
Synonyms | Protein NKG-5, Lymphokine LAG-2, GNLY, LAG2, NKG5, TLA519 |
Reference Data | |
Protein Families | Secreted Protein |
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