RND3 (1-245) Mouse Monoclonal Antibody [Clone ID: 1D2]

CAT#: AM31720PU-N

RND3 (1-245) mouse monoclonal antibody, clone 1D2, Purified

Product Images

Detection limit for recombinant GST tagged RND3 is 0.3 ng/ml as a capture antibody.

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  Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 1D2
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 10 µg/ml.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: RND3 antibody was raised against RND3 (AAH12513, 1 a.a. ~ 245 a.a) full-length recombinant protein with GST tag.
• Specificity: Recognizes RND3 / ARHE.
• Formulation: PBS, pH 7.4
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A Chromatography
• Storage: Store the antibody (in aliquots) at -20°C or -80°C.
  Avoid freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens Rho family GTPase 3 (RND3), transcript variant 2
• Database Link:
  Entrez Gene 390 Human
• Background: Rho-related GTP-binding protein RhoE, also known as RND3, is a small GTPase of the Ras superfamily that regulate the organization of the actin cytoskeleton in response to extracellular growth factors. RND3 activity leads to a decrease in stress fibers and increased cell migration, at least in part through regulation of the Rho-dependent kinase ROCK1. Also, RND3 has been implicated in inhibition of DNA-damage induced apoptosis and cell cycle arrest.
• Synonyms: RHO8, RHOE, MemB protein