SERCA3 (ATP2A3) Mouse Monoclonal Antibody [Clone ID: 2H3]

CAT#: AM31724PU-N

SERCA3 (ATP2A3) mouse monoclonal antibody, clone 2H3, Purified

Product Images

Western Blot analysis of ATP2A3 expression in HL-60 cell lysate.

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  Detection limit for recombinant GST tagged ATP2A3 is approximately 0.3ng/ml as a capture antibody.

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  Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 2H3
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: ATP2A3 antibody was raised against ATP2A3 (AAH35729, 501 a.a. ~ 621 a.a) partial recombinant protein with GST tag.
• Specificity: Recognizes ATP2A3 / SERCA3
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: 0.5 mg/ml
• Purification: Protein A Chromatography
• Gene Name: Homo sapiens ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 (ATP2A3), transcript variant 1
• Database Link:
  Entrez Gene 489 Human
• Background: ATP2A3 belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. Transports calcium ions from the cytosol into the sarcoplasmic/endoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction.
  Found in most tissues. Most abundant in thymus, trachea, salivary gland, spleen, bone marrow, lymph node, peripheral leukocytes, pancreas and colon. Also detected in fetal tissues.
• Synonyms: Calcium pump 3 ATPase

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Alzheimer's disease, Calcium signaling pathway