CBSL Mouse Monoclonal Antibody [Clone ID: 6B8]

CAT#: AM31731PU-N

CBSL mouse monoclonal antibody, clone 6B8, Purified

Product Images

Detection limit for recombinant GST tagged CBS is approximately 0.3ng/ml as a capture antibody.

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  Human Brain, Cerebellum: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 6B8
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: CBS (NP_000062, 1 a.a. ~ 101 a.a) partial recombinant protein with GST tag.
• Specificity: Recognizes Human CBS.
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction
• Purification: Protein A Chromatography
• Gene Name: Homo sapiens cystathionine-beta-synthase (CBS), transcript variant 1
• Database Link:
  Entrez Gene 102724560 Human
• Background: CBS is involved in transsulfuration pathway. The first step of this pathway, from homocysteine to cystathionine, is catalyzed by CBS. CBS deficiency can cause homocystinuria which affects many organs and tissues including the eyes, the central nervous, skeletal, and vascular systems.
• Synonyms: Cystathionine beta-synthase, Serine sulfhydrase, Beta-thionase

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Cysteine and methionine metabolism, Glycine, serine and threonine metabolism, Metabolic pathways, Selenoamino acid metabolism