CTIP1 (BCL11A) Mouse Monoclonal Antibody [Clone ID: 3D9]

CAT#: AM31750PU-N

CTIP1 (BCL11A) mouse monoclonal antibody, clone 3D9, Purified

Product Images

Western Blot analysis of BCL11A expression in transfected 293T cell line by BCL11A monoclonal antibody, clone 3D9.

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  Human Heart: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 3D9
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG2a
• Clonality: Monoclonal
• Immunogen: BCL11A (NP_060484, 1 a.a. ~ 89 a.a) partial recombinant protein with GST tag.
• Specificity: Recognizes Bcl-11A
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: 1 mg/ml
• Purification: Protein A Chromatography
• Gene Name: Homo sapiens B-cell CLL/lymphoma 11A (BCL11A), transcript variant 2
• Database Link:
  Entrez Gene 53335 Human
• Background: This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.
• Synonyms: BCL11A, CTIP1, EVI9, KIAA1809

Reference Data

• Protein Families: Transcription Factors