SRP1 (KPNA1) Mouse Monoclonal Antibody [Clone ID: 2A4-1B5]

CAT#: AM31805PU-N

SRP1 (KPNA1) mouse monoclonal antibody, clone 2A4-1B5, Purified

Product Images

Western Blot analysis of KPNA1 expression in HeLa cell lysate.

• 

  Western Blot analysis of KPNA1 expression in transfected 293T cell line by KPNA1 monoclonal antibody.

• 

  Detection limit for recombinant GST tagged KPNA1 is approximately 1ng/ml as a capture antibody.

• 

  Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 2A4-1B5
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: KPNA1 antibody was raised against kPNA1 (AAH02374, 1 a.a. ~ 539 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
• Specificity: This antibody reacts to KPNA1 / SRP1.
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage: Store the antibody at -20°C to -80°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens karyopherin subunit alpha 1 (KPNA1), transcript variant 1
• Database Link:
  Entrez Gene 3836 Human
• Background: Recombination activating proteins RAG1 and RAG2 regulate and mediate V(D)J recombination, the process by which genes for immunoglobulins and T-cell receptors are generated. Several other ubiquitously expressed proteins are thought to be recruited in the recombination process. Among these are the genes affected in severe combined immune deficiency and genes involved in ds-DNA break repair. The KPNA1 product interacts with RAG1 and may play a role in V(D)J recombination.
• Synonyms: Karyopherin alpha 1, SRP1, SRP1-beta, RCH2, IPOA5, NPI-1, Nucleoprotein interactor 1