ATP6V1B2 Mouse Monoclonal Antibody [Clone ID: 2A5]

CAT#: AM31923PU-N

ATP6V1B2 mouse monoclonal antibody, clone 2A5, Purified

Product Images

Western Blot analysis of ATP6V1B2 expression in transfected 293T cell line by ATP6V1B2 monoclonal antibody, clone 2A5.

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  Human Kidney, Tubules: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Clone Name: 2A5
• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant protein
• Specificity: This antibody recognizes Human ATP6V1B2.
• Formulation: PBS, pH 7.2
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Protein A Chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens ATPase H+ transporting V1 subunit B2 (ATP6V1B2)
• Database Link:
  Entrez Gene 526 Human
• Background: ATP6V1B2 (ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2) is a non-catalytic subunit of the vacuolar ATPase (V-ATPase) responsible for acidifying a variety of intracellular compartments, and for the pH regulation of extracellular compartments. V-ATPase is a heteromultimeric enzyme composed of a peripheral catalytic V1 complex (subunits A-H) attached to an integral membrane V0 proton pore complex. The localisation of ATP6V1B2 to the olfactory epithelium has been studied due to the potential role of pH regulation of extracellular compartments in olfaction.
• Synonyms: V-ATPase subunit B 2, ATP6B2, VPP3, HO57

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Epithelial cell signaling in Helicobacter pylori infection, Metabolic pathways, Oxidative phosphorylation, Vibrio cholerae infection