PNPO Mouse Monoclonal Antibody [Clone ID: AT2C7]

CAT#: AM39001PU-S

PNPO mouse monoclonal antibody, clone AT2C7, Purified

Product Images

The extracts of HepG2 (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PNPO (1:500 ~ 1:5000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

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  Western blot analysis: The extracts of HepG2 (40 ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PNPO (1:500 ~ 1:5000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system.

Specifications

Product Data

• Clone Name: AT2C7
• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Western blot (1:500 - 1:5000).
• Reactivities: Human
• Host: Mouse
• Isotype: IgG1
• Clonality: Monoclonal
• Immunogen: Recombinant human PNPO (57-261aa) purified from E. coli
• Specificity: Teh antibody recognizes human PNPO. Other species not tested.
• Formulation: PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Protein-G affinity chromatography
• Gene Name: Homo sapiens pyridoxamine 5'-phosphate oxidase (PNPO)
• Database Link:
  Entrez Gene 55163 Human
• Background: PNPO (pyridoxamine 5'-phosphate oxidase) is a 261 amino acid protein belonging to the pyridoxamine 5'-phosphate oxidase family. It is the rate-limiting enzyme in vitamin B6 synthesis. Vitamin B6 (Pyridoxal 5-prime-phosphate or PLP) is vital for normal cellular function, and some cancer cells have notable differences in vitamin B6 metabolism compared to their normal counterparts. Vitamin B6 is a required co-factor for enzymes involved in both homocysteine metabolism and synthesis of neurotransmitters such as catecholamine.
• Synonyms: FLJ10535; PDXPO

Reference Data

• Protein Pathways: Metabolic pathways, Vitamin B6 metabolism