CDK4 Mouse Monoclonal Antibody [Clone ID: AT6D10]

CAT#: AM50057PU-S

CDK4 mouse monoclonal antibody, clone AT6D10, Purified


USD 230.00

2 Weeks*

Size
    • 50 ul

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Specifications

Product Data
Clone Name AT6D10
Applications ELISA, WB
Recommended Dilution The antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results. Recommended starting dilution is 1:500.
Reactivities Human
Host Mouse
Isotype IgG2a
Clonality Monoclonal
Immunogen Recombinant human CDK4 (1-303aa) purified from E. coli
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration lot specific
Purification Protein-A affinity chromatography
Storage Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C for longer.
Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens cyclin-dependent kinase 4 (CDK4)
Background Cyclin-dependent kinase 4, also known as CDK4, belongs to the cyclin-dependent kinases (CDK) family. CDKs are a family of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells. CDK4, in complex with D-type cyclins, is thought to regulate cell growth during the G1 phase of the cell cycle. This association with a D-type cyclin up-regulates CDK4 activity, whereas binding to the CDK inhibitor p16 down-regulates CDK4 activity.
Synonyms PSK-J3
Reference Data
Protein Families Druggable Genome, Protein Kinase
Protein Pathways Bladder cancer, Cell cycle, Chronic myeloid leukemia, Glioma, Melanoma, Non-small cell lung cancer, p53 signaling pathway, Pancreatic cancer, Pathways in cancer, Small cell lung cancer, T cell receptor signaling pathway, Tight junction

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.