RAIDD (CRADD) Mouse Monoclonal Antibody [Clone ID: AT14G8]

CAT#: AM50351PU-S

RAIDD (CRADD) mouse monoclonal antibody, clone AT14G8, Purified


USD 230.00

2 Weeks*

Size
    • 50 ul

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Specifications

Product Data
Clone Name AT14G8
Applications ELISA, WB
Recommended Dilution This antibody has been tested by ELISA, Western blot analysis to assure specificity and reactivity.
Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Recommended Starting Dilution: 1/500.
Reactivities Human
Host Mouse
Isotype IgG1
Clonality Monoclonal
Immunogen Recombinant Human CRADD (1-199aa) purified from E. coli.
Formulation PBS, pH 7.4 containing 0.02% Sodium Azide and 10% Glycerol
State: Purified
State: Liquid purified Ig fraction
Concentration 1.0 mg/ml
Purification Affinity Chromatography on Protein A
Gene Name Homo sapiens chitinase 3 like 1 (CHI3L1)
Background CRADD, also referred as RAIDD, is an adaptor protein that could interact with both caspase 2 and RIP that can promote apoptosis once activated. RAIDD (RIP-associated ICH-1/Ced-3 homologous protein with a death domain) has been identified as a RIP binding protein that also associates with members of the caspase family, providing a link between activation of the TNF-Rs and the triggering of the cysteine protease cascade. The amino-terminal domain of RAIDD shares significant homology with the prodomain of ICH-1 and mediates the binding of RAIDD to this cysteine protease.
Synonyms CRADD
Reference Data
Protein Families Secreted Protein

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.