Cytochrome P450 2E1 (CYP2E1) Rabbit Polyclonal Antibody

CAT#: AP00032PU-N

Cytochrome P450 2E1 (CYP2E1) rabbit polyclonal antibody, Aff - Purified

Product Images

Cytochrome P450 antibody staining of Rat kidney tissue lysate by Western blotting.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blot: 0.5-4 μg/ml.
• Reactivities: Canine, Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide surrounding amino acid 405 of Human Cytochrome P450.
• Specificity: The antibody detects ~58kDa cytochrome P450 IIE1.
• Formulation: PBS containing 30% Glycerol, 0.5% BSA and 0.01% Thimerosal as preservative.
  State: Aff - Purified
  State: Liquid purified IgG fraction.
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Upon receipt, store (in aliquots) at -20°C to -80°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens cytochrome P450 family 2 subfamily E member 1 (CYP2E1)
• Database Link:
  Entrez Gene 13106 MouseEntrez Gene 25086 RatEntrez Gene 1571 Human
• Background: Cytochrome P450 is mainly found in liver, and can metabolize a wide range of compounds such as organic solvents, acetaminophen, dimethylnitrosoamine and aliphatic alcohol, which have certain toxicological effects in humans. Ethanol-induced cytochrome P450 IIE1 is considered to be one of the major causes of oxidative stress in the liver following ethanol treatment.
• Synonyms: Cytochrome P450 2E1, CYP2E, CYPIIE1, Cytochrome P450-J
• Note: Blocking peptide (Cat.#AP00032CP-N) is available separately.

Reference Data

• Protein Families: Druggable Genome, P450, Transmembrane
• Protein Pathways: Arachidonic acid metabolism, Drug metabolism - cytochrome P450, Linoleic acid metabolism, Metabolic pathways, Metabolism of xenobiotics by cytochrome P450