Collagen VI (COL6A1) Goat Polyclonal Antibody

CAT#: AP00361PU-N

Collagen VI (COL6A1) goat polyclonal antibody, Purified

Specifications

Product Data

• Applications: ELISA, IF, IHC, WB
• Recommended Dilution: ELISA.
  Immunoblotting.
  Immunofluorescence.
  Immunohistochemistry on Frozen Sections.
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen:
  Human type VI collagen. Antiserum to human type VI collagen was raised by repeated immunisation of goats with highly purified antigen.
• Specificity: This antibody recognizes Human type VI Collagen and exhibits < 10% cross reactivity with Collagen types I, II, III, IV and V
• Formulation: Borate buffered saline
  State: Purified
  State: Liquid purified IgG fraction
  Stabilizer: None
  Preservative: None
• Concentration: lot specific
• Purification: Affinity Chromatography
• Storage: Upon receipt, store undiluted (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens collagen type VI alpha 1 chain (COL6A1)
• Database Link:
  Entrez Gene 1291 Human
• Background: Type V Collagen is a member of group I Collagen (fibrillar forming collagen). It is a minor connective tissue component of nearly ubiquitous distribution. Type V Collagen binds to DNA, heparan sulfate, Thrombospondin, Heparin, and Insulin. Collagen V is composed of several subunits as follows: trimers of two alpha 1(V) and one alpha 2(V) chains in most tissues and trimers of one alpha 1(V), one alpha 2(V), and one alpha 3(V) chains in placenta. Type V Collagen is closely related to type XI Collagen and it is possible that the Collagen chains of types V and XI constitute a single collagen type with tissue specific chain combinations. Mutations in this gene are associated with Ehlers Danlos syndrome, types I and II.
• Synonyms: COL6A1

Reference Data

• Protein Pathways: ECM-receptor interaction, Focal adhesion