NPY1R Rabbit Polyclonal Antibody

CAT#: AP01221PU-N

NPY1R rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of NPY1-R antibody in extracts from NIH-3T3 cells.

Specifications

Product Data

• Applications: IF, WB
• Recommended Dilution: Western Blot: 1/500-1/1000.
  Immunofluorescence: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 225-270 of Human NPY1-R.
• Specificity: This antibody detects endogenous levels of Neuropeptide Y Receptor 1 (NPY1-R) protein. (region surrounding Arg254)
• Formulation: Phosphate buffered saline (PBS), pH~7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE)
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: ~44 kDa
• Gene Name: Homo sapiens neuropeptide Y receptor Y1 (NPY1R)
• Database Link:
  Entrez Gene 18166 MouseEntrez Gene 29358 RatEntrez Gene 4886 Human
• Background: Neuropeptide Y (NPY) is one of the most abundant neuropeptides in the mammalian nervous system and exhibits a diverse range of important physiologic activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system. There are two major subtypes of NPY (Y1 and Y2). The NPY Y1 receptors have been identified in a variety of tissues, including brain, spleen, small intestine, kidney, testis, placenta, breast, colon, ganglion, heart, and aortic smooth muscle. The Y2 receptor is found mainly in the central nervous system. NPY receptors are a member of the G protein-coupled receptor superfamily.
• Synonyms: NPYR, NPYY1, Neuropeptide Y receptor 1

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction