PPP2R5D Rabbit Polyclonal Antibody

CAT#: AP05044PU-N

PPP2R5D rabbit polyclonal antibody, Purified

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western Blotting.
  Immunofluorescence.
• Reactivities: Bovine, Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide conjugated to KLH derived from the N-terminus of PP2A/B delta
• Specificity: This antibody reacts to PP 2A/B delta.
• Formulation: Phosphate buffered saline with 0.08% sodium azide
  State: Purified
  State: Liquid purified Ig (0.2 µm sterile filtered)
• Concentration: lot specific
• Storage: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens protein phosphatase 2 regulatory subunit B'delta (PPP2R5D), transcript variant 1
• Database Link:
  Entrez Gene 21770 MouseEntrez Gene 363193 RatEntrez Gene 5528 Human
• Background: PP2A is a heterotrimeric phosphatase, ccomposed of A, B and C subunits. The structural A and catalytic C subunits form the constitutive core of the enzyme, which associates with one of a large number of regulatory B subunits. Three families of B subunits have been identified thus far. The prototypical B (or PR55) family of subunits is encoded by three genes, Ba, Bb and Bg . The B' (or B56) family consists of at least seven splice variants derived from five genes. RNA's for the two members of the B family, PR72 and PR130, arise by alternative splicing or use of alternate transcription start sites from the same gene. Primary structures as well as functions of B and B' subunits are conserved from yeast to mammals. Bd is a novel isoform of the B class of PP2A regulatory subunits. It is widely expressed in rat tissues and appears to be involved in targeting PP2A to the cytosolic compartment.
• Synonyms: Protein phosphatase 2A, PP2A B subunit B'delta isoform, PP2A B subunit B56 delta isoform, PP2A B subunit PR61 delta isoform, PP2A B subunit R5 delta isoform

Reference Data

• Protein Families: Phosphatase
• Protein Pathways: Oocyte meiosis, Wnt signaling pathway