SGPL1 Rabbit Polyclonal Antibody
Other products for "SGPL1"
Specifications
Product Data | |
Applications | WB |
Recommended Dilution | Western Blot: 1/400. Positive Control: Madin-Darby Bovine Kidney (MDBK) cell lysate. |
Reactivities | Bovine, Human, Mouse, Rat |
Host | Rabbit |
Isotype | IgG |
Clonality | Polyclonal |
Immunogen | Synthetic peptide derived from the sphingosine 1-phosphate lyase 1 protein. |
Specificity | This antibody recognizes Sphingosine 1-Phosphate Lyase 1. |
Formulation | PBS State: Aff - Purified State: Liquid purified IgG fraction Preservative: 0.08% Sodium Azide |
Concentration | Lot specific |
Purification | Antigen Immunoaffiinity Chromatography |
Gene Name | Homo sapiens sphingosine-1-phosphate lyase 1 (SGPL1) |
Database Link | |
Background | Sphingosine-1-phosphate lyase cleaves phosphorylated sphingoid bases, such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. The catalytic activity of sphingosine 1-phosphate lyase converts sphingosine 1-phosphate to phosphoethanolamine and palmitaldehyde using Pyridoxal phosphate as a co-factor. Sphingosine 1-phosphate lyase is a type III membrane protein found in the endoplasmic reticulum. Sphingosine 1-phosphate lyase is found primarily in the liver and kidney. Sphingosine 1-phosphate lyase belongs to the group II decarboxylase family. |
Synonyms | SP-lyase 1, SPL 1, Sphingosine-1-phosphate aldolase, Sphingosine-1-phosphate lyase 1, KIAA1252 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Metabolic pathways, Sphingolipid metabolism |
Documents
Product Manuals |
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