Sphingomyelin Synthase 1 (SGMS1) Rabbit Polyclonal Antibody

CAT#: AP05206PU-N

Sphingomyelin Synthase 1 (SGMS1) rabbit polyclonal antibody, Purified

Specifications

Product Data

• Applications: ELISA, WB
• Recommended Dilution: ELISA.
  Western Blot: 5 - 10 µg/ml.
  Positive Control: Brain, heart, kidney, liver, muscle and stomach.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide derived from the mouse sphingomyelin synthase 1 protein
• Specificity: This antibody reacts to Sphingomyelin Synthase 1.
• Formulation: Phosphate buffered saline, pH 7.4
  State: Purified
  State: Liquid purified Ig
• Concentration: Lot specific
• Gene Name: Homo sapiens sphingomyelin synthase 1 (SGMS1)
• Database Link:
  Entrez Gene 259230 Human
• Background: A bidirectional lipid cholinephosphotransferases capable of converting phosphatidylcholine (PC) and ceramide to sphingomyelin (SM) and diacylglycerol (DAG) and the inverse reaction. Direction is dependent on the relative concentrations of DAG and ceramide as phosphocholine acceptors. Directly and specifically recognizes the choline head group on the substrate. Also requires two fatty chains on the choline-P donor molecule in order to be recognized efficiently as a substrate. May not function strictly as a SM synthase. Inhibited by bacterial PC-phospholipase C inhibitor D609. Localized to Golgi apparatus; Golgi membrane; multi-pass membrane protein. Possibly present on Brain, heart, kidney, liver, muscle and stomach.
• Synonyms: Transmembrane protein 23, SMS1, Sphingomyelin synthase 1, MOB, Medulla oblongata-derived protein

Reference Data

• Protein Families: Transmembrane
• Protein Pathways: Metabolic pathways, Sphingolipid metabolism