Col1a1 Rabbit Polyclonal Antibody

CAT#: AP05388PU-N

Col1a1 rabbit polyclonal antibody, Purified


USD 530.00

5 Days*

Size
    • 100 ul

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Specifications

Product Data
Applications ELISA, IF, IHC, R
Recommended Dilution ELISA: 1/100-1/400.
Immunofluorescence: 1/50-1/100.
Radioimmunoassays.
Immunohistochemistry on Frozen Sections.
Immunohistochemistry on Paraffin Sections: 1/250-1/1000.
Reactivities Mouse
Host Rabbit
Isotype IgG
Clonality Polyclonal
Immunogen Native type I Collagen from Mouse skin.
Specificity This antibody is specific for Mouse Collagen type I.
Less than 1% cross reactivity has been observed with Mouse Collagen, types II, VI and III and Human, Chicken and Rat Collagen, type I.
Formulation Phosphate buffered saline containing 0.09% Sodium Azide as preservative.
State: Purified
State: Liquid purified Ig fraction
Purification Affinity Chromatography
Gene Name Mus musculus collagen, type I, alpha 1 (Col1a1)
Background Collagens are highly conserved throughout evolution and are characterised by an uninterrupted "Glycine X Y" triplet repeat that is a necessary part of the triple helical structure. Type I collagen (95 kDa) is found in bone, cornea, skin and tendon. Mutations in the encoding gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for Platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor.
Synonyms COL1A1, COL1A2, Alpha-1 type I collagen, Alpha-2 type I collagen
Reference Data

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.