Cytokeratin 3 (KRT3) Guinea Pig Polyclonal Antibody

CAT#: AP09551SU-N

Cytokeratin 3 (KRT3) guinea pig polyclonal antibody, Serum

Specifications

Product Data

• Applications: IF, IHC
• Recommended Dilution: Immunofluorescence.
  Immunohistchemistry on Frozen Sections: 1/100-1/200.
  Incubation Time: 1h at RT.
  Positive Control: Human cornea.
• Reactivities: Human, Mouse
• Host: Guinea Pig
• Clonality: Polyclonal
• Immunogen: Synthetic peptide of Human keratin K3 (formerly also designated cytokeratin 3; C- IKF SQS SQS SQR YSR), coupled to KLH
• Specificity: MW 63,000 (pI 7.5) intermediate filament polypeptide, keratin K3, detected by Immunohistochemistry in the cornea only.
  Useful as a marker for corneal type differentiation (positive for epithelial cells of cornea) and for studying corneal epithelial stem cells.
• Formulation: State: Serum
  State: Liquid Serum
  Preservative: 0.09% Sodium Azide
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens keratin 3 (KRT3)
• Database Link:
  Entrez Gene 3850 Human
• Background: Cytokeratin 3 belongs to the intermediate filament family. It is a type II cytokeratin and is specifically expressed in the corneal epithelium. Cytokeratin 3 associates with Cytokeratin 12. Defects in Cytokeratin 3 are a cause of Meesmann corneal dystrophy.
• Synonyms: Keartin-3, KRT3, Type-II keratin Kb3