Lysozyme (LYZ) Rabbit Polyclonal Antibody

CAT#: AP10434PU-N

Lysozyme (LYZ) rabbit polyclonal antibody, Purified

Product Images

Formalin-Fixed, Paraffin-Embedded Human granulocytic sarcoma involving skin stained with Lysozyme antibody Cat.-No. AP10434PU-N using peroxidase conjugate and DAB chromogen. Note the cytoplasmic staining of tumor cells.

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Sections: 1/50-1/200
  Pretreatment of tissue with proteolytic enzymes should be performed prior to staining.
  Use Polymer anti Mouse/Rabbit IgG as a detection system.
  Positive Control: Myeloid leukemia.
• Reactivities: Canine, Feline, Human, Monkey, Porcine
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Human Lysozyme purified from the urine of patients with monocytic leukemia.
• Specificity: The antibody was adsorbed with Human plasma and urine proteins to remove the cross-reacting antibodies. It labels myeloid cells, histiocytes, granulocytes, macrophages, and monocytes. This antibody is helpful in the identification of myeloid or monocytic nature of acute leukemia.
  Cellular Localization: Cytoplsmic.
• Formulation: State: Purified
  State: Liquid purified IgG fraction with 0.2% BSA and 15mM Sodium Azide.
• Storage: Store the antibody undiluted at 2-8°C.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens lysozyme (LYZ)
• Database Link:
  Entrez Gene 4069 Human
• Background: Lysozyme catalyzes the hydrolysis of certain mucopolysaccharides of bacterial cell walls. Specifically, it catalyzes the hydrolysis of the bacterial cell wall beta glycosidic linkages between N acetylmuramic acid and N acetylglucosamine. It is found in spleen, lung, kidney, white blood cells, plasma, saliva, milk, and tears. Lysozyme is synthesized predominantly in reactive histiocytes rather than in resting, unstimulated phagocytes.
• Synonyms: LYZ, LZM

Reference Data

• Protein Families: Druggable Genome