beta 2 Adrenergic Receptor (ADRB2) Rabbit Polyclonal Antibody

CAT#: AP13972PU-N

beta 2 Adrenergic Receptor (ADRB2) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of anti-BAR2 Antibody in mouse kidney lysates (35 ug/lane). BAR2 (arrow) was detected using the purified Pab (1:60 dilution).

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  Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with BAR2 Antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1,000.
  Western blot: 1/1,000.
  Immunohistochemistry on Paraffin sections: 1/10-1/50.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to 236-264 amino acid residues surrounding S261 of human BAR2.
• Specificity: This antibody detetcs BAR2.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) Sodium Azide
• Concentration: lot specific
• Purification: Protein A column, followed by peptide affinity purification.
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: adrenoceptor beta 2
• Database Link:
  Entrez Gene 154 Human
  UniProt ID P07550
• Background: Beta-2-adrenergic receptor is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor.
• Synonyms: ADRB2, ADRB2R, B2AR, Beta-2 adrenoreceptor
• Note: Molecular weight: 46459 Da