CBSL Rabbit Polyclonal Antibody

CAT#: AP17189PU-N

CBSL rabbit polyclonal antibody


USD 450.00

2 Weeks*

Size
    • 400 ul

Product Images

Specifications

Product Data
Applications WB
Recommended Dilution Western blot: 1:100 - 1:500.
ELISA: 1:1,000.
Reactivities Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen KLH conjugated synthetic peptide selected from the Center region of human CBS
Specificity This antibody detects CBS at Center.
Formulation PBS with 0.09% (W/V) sodium azide
State: Liquid Ig fraction
Concentration lot specific
Purification Purified through a protein A column, followed by peptide affinity purification
Conjugation Unconjugated
Storage Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Stability Shelf life: one year from despatch.
Gene Name Homo sapiens cystathionine-beta-synthase (CBS), transcript variant 1
Background CBS acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. This protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria.
Synonyms Cystathionine beta-synthase, Serine sulfhydrase, Beta-thionase
Note Molecular weight: 60587 Da
Reference Data
Protein Families Druggable Genome
Protein Pathways Cysteine and methionine metabolism, Glycine, serine and threonine metabolism, Metabolic pathways, Selenoamino acid metabolism

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.