FMO3 (N-term) Rabbit Polyclonal Antibody

CAT#: AP17395PU-N

FMO3 (N-term) rabbit polyclonal antibody

Product Images

Western blot analysis of FMO3 Antibody (N-term) in MDA-MB231 cell line lysates (35 ug/lane). FMO3 (arrow) was detected using the purified Pab.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1:100 - 1:500.
  ELISA: 1:1,000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human FMO3
• Specificity: This antibody detects FMO3 at N-term.
• Formulation: PBS with 0.09% (W/V) sodium azide
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Purified through a protein A column, followed by peptide affinity purification
• Storage: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens flavin containing monooxygenase 3 (FMO3), transcript variant 2
• Database Link:
  Entrez Gene 2328 Human
• Background: FMO3 is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides. It N-oxygenates primary aliphatic alkylamines as well as secondary and tertiary amines. It plays an important role in the metabolism of trimethylamine (TMA), via the production of TMA N-oxide (TMAO). Is also able to perform S-oxidation when acting on sulfide compounds.
• Synonyms: FMO form 2, FMO II, Dimethylaniline oxidase 3
• Note: Molecular weight: 60033 Da

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Drug metabolism - cytochrome P450