RACGAP1 Rabbit Polyclonal Antibody

CAT#: AP20256PU-N

RACGAP1 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of MgcRacGAP antibody (AP20256PU-N) in extracts from COS7 cells.

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  Immunohistochemistry analyzes of MgcRacGAP antibody (AP20256PU-N) in paraffin-embedded human brain tissue.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunohistochemistry on paraffin sections: 1/50-1/200.
  Immunoflourescence: 1/50-1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of MgcRacGAP protein.
• Formulation: Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity-chromatography using epitope-specific immunogen; purity is > 95% (by SDS-PAGE)
• Predicted Protein Size: ~ 72 kDa
• Gene Name: Homo sapiens Rac GTPase activating protein 1 (RACGAP1), transcript variant 2
• Database Link:
  Entrez Gene 26934 MouseEntrez Gene 315298 RatEntrez Gene 29127 Human
• Background: Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
• Synonyms: MGCRACGAP, KIAA1478

Reference Data

• Protein Families: Druggable Genome