CYB5R3 Rabbit Polyclonal Antibody

CAT#: AP20483PU-N

CYB5R3 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of Cytochrome b5 antibody (Cat.-No.: AP20483PU-N) in extracts from A549 cells.

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  Immunohistochemistry (IHC) analyzes of Cytochrome b5 antibody (Cat.-No.: AP20483PU-N) in paraffin-embedded human heart tissue.

Specifications

Product Data

• Applications: IF, IHC, WB
• Recommended Dilution: Western blot: 1/500 - 1/1000.
  Immunohistochemistry on paraffin sections: 1/50 - 1/200.
  Immunofluorescence: 1/50 - 1/200.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of Cytochrome b5protein.
  (region surrounding Gly82)
• Formulation: Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography (> 95% (by SDS-PAGE)
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 15 kDa
• Gene Name: Homo sapiens cytochrome b5 reductase 3 (CYB5R3), transcript variant 1
• Database Link:
  Entrez Gene 25035 RatEntrez Gene 109754 MouseEntrez Gene 1727 Human
• Background: Cytochrome b5 is a membrane-bound member of the cytochrome b family. A heme protein that functions as an electron carrier for many membrane-bound oxygenases, cytochrome b5 possesses two heme groups, which are not covalently attached to the protein. Two isoforms of cytochrome b5, a microsomal membrane-bound form and a cytoplasmic form, are produced by alternative splicing. Mutations in cytochrome b5 are associated with Leber’s hereditary optic neuropathy and with myopathy.
• Synonyms: NADH-cytochrome b5 reductase 3, B5R, DIA1, Diaphorase-1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Amino sugar and nucleotide sugar metabolism