c-Myb (MYB) Rabbit Polyclonal Antibody

CAT#: AP21138PU-N

c-Myb (MYB) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of c-Myb antibody (Cat.-No.: AP21138PU-N) in extracts from 293 cells.

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  Immunohistochemistry (IHC) analyzes of c-Myb antibody (Cat.-No.: AP21138PU-N) in paraffin-embedded human breast carcinoma tissue.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: 1/500-1/1000.
  Immunohistochemistry on Paraffin Sections: 1/50-1/200.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide, corresponding to amino acids 491-540 of Human c-Myb.
• Specificity: This antibody detects endogenous levels of c-Myb protein.
  (region surrounding Ile526)
• Formulation: Phosphate buffered saline (PBS), pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% (by SDS-PAGE)
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 80 kDa
• Gene Name: Homo sapiens v-myb avian myeloblastosis viral oncogene homolog (MYB), transcript variant 2
• Database Link:
  Entrez Gene 17863 MouseEntrez Gene 4602 Human
• Background: c-Myb is the cellular homolog of the leukemogenic avian retroviral protein v-Myc. c-Myb is expressed predominantly in immature and rapidly dividing hematopoietic cells, and cellular levels of c-Myb substantially decreases as cells reach terminal differentiation. B-Myb is expressed in a wide variety of proliferating cells, with levels accumulating during the G1 to S phase transition. A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes.
• Synonyms: c-Myb

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transcription Factors