EFEMP1 Rabbit Polyclonal Antibody

CAT#: AP21171PU-N

EFEMP1 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of Fibulin-3 antibody (Cat.-No.: AP21171PU-N) in extracts from rat lung cells.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/500 - 1/1000.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of Fibulin-3 protein.
  (region surrounding Pro150)
• Formulation: Phosphate buffered saline (PBS), pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 55 kDa
• Gene Name: Homo sapiens EGF containing fibulin-like extracellular matrix protein 1 (EFEMP1), transcript variant 2
• Database Link:
  Entrez Gene 216616 MouseEntrez Gene 305604 RatEntrez Gene 2202 Human
• Background: Fibulin-3, also known as EFEMP1, is a secreted protein. Defects in the gene for Fibulin-3 cause the autosomal dominant disease Doyne honeycomb retinal dystrophy (DHRD, also known as malattia leventinese) which is characterized by yellow-white deposits (drusen) that accumulate under the retinal pigment epithelium. Fibulin-3 is not present at the site of drusen formation in normal eyes. Fibulin-5 is an integrin-binding extracellular matrix protein that mediates endothelial cell adhesion.
• Synonyms: DHRD, DRAD, FBNL, MLVT, MTLV, S1-5, Fibulin 3, EFEMP1, FBLN3

Reference Data

• Protein Families: Secreted Protein