AGFG2 Rabbit Polyclonal Antibody

CAT#: AP21188PU-N

AGFG2 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of Rabr antibody (Cat.-No.: AP21188PU-N) in extracts from MCF-7cells.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/500-1/1000.
• Reactivities: Human, Mouse
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of Rabr protein.
  (region surrounding Val131)
• Formulation: Phosphate buffered saline (PBS), pH~7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction (> 95% pure by SDS-PAGE).
  Preservative: 0.05% Sodium Azide
• Concentration: 1.0 mg/ml
• Purification: Affinity Chromatography using epitope-specific immunogen.
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 49 kDa
• Gene Name: Homo sapiens ArfGAP with FG repeats 2 (AGFG2)
• Database Link:
  Entrez Gene 231801 MouseEntrez Gene 3268 Human
• Background: Rabr, also known as AGFG2 (Arf-GAP domain and FG repeats-containing protein 2), is a 481 amino acid member of the HIV-1 REV binding protein (HRB) family and has one Arf-GAP zinc finger domain, several phe-gly (FG) motifs, and four asn-pro-phe (NPF) motifs. Rabr shares 46% identity with Rab. Both Rab and Rabr contain a zinc finger region near the N terminus, several phe-gly (FG) motifs, which is characteristic of nucleoporin-like proteins, and four NPF motifs located in the C-terminal region. Rabr interacts with Eps15 homology (EH) domains and plays a role in the REV export pathway, which mediates the nucleocytoplasmic transfer of proteins and RNAs.
• Synonyms: HIV-1 Rev-binding protein-like protein, RABR