PTGR1 Rabbit Polyclonal Antibody

CAT#: AP21197PU-N

PTGR1 rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot (WB) analysis of LTB4DH antibody (Cat.-No.: AP21197PU-N) in extracts from HT-29 cells.

Specifications

Product Data

• Applications: WB
• Recommended Dilution: Western blot: 1/500 - 1/1000.
• Reactivities: Human
• Host: Rabbit
• Clonality: Polyclonal
• Specificity: This antibody detects endogenous levels of LTB4DH protein.
  (region surrounding Leu105)
• Formulation: Phosphate buffered saline (PBS), pH 7.2
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.05% sodium azide
• Concentration: 1.0 mg/ml
• Purification: Affinity chromatography using epitope-specific immunogen (> 95% pure by SDS-PAGE)
• Conjugation: Unconjugated
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Predicted Protein Size: ~ 36 kDa
• Gene Name: Homo sapiens prostaglandin reductase 1 (PTGR1), transcript variant 2
• Database Link:
  Entrez Gene 22949 Human
  UniProt ID Q14914
• Background: The NADP(H)-dependent enzyme leukotriene 12-hydroxy dehydrogenase (LTB4DH) catalyzes double bond reductions and oxo-reductions in lipoxins (15-oxo-lipoxin A 4 ), leukotrienes (leukotriene B 4 ) and E/F prostaglandins (15-oxo prostaglandins). The reactions mediated by LTB4DH constitute an important inactivation pathway for these key lipid mediators involved in inflammation. LTB4DH belongs to the medium-chain dehydrogenase/reductase enzyme family.
• Synonyms: PTGR1, LTB4DH, PGR-1, PGR1

Reference Data

• Protein Families: Druggable Genome