IRF6 (455-467) Goat Polyclonal Antibody

CAT#: AP22529PU-N

IRF6 (455-467) goat polyclonal antibody, Aff - Purified

Product Images

Antibody staining (0.2 ug/ml) of Human Ovary lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

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  Human Kidney (formalin-fixed, paraffin-embedded) stained with IRF6 antibody at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

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  Human Prostate (formalin-fixed, paraffin-embedded) stained with IRF6 antibody at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 2.5 µg/ml.
  Western Blot: 0.2 - 1 µg/ml.
• Reactivities: Human
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from C-term of human IRF6
• Specificity: This antibody detects IRF6 at aa 455-467.
• Formulation: Tris saline buffer, pH 7.3, 0.5% BSA, 0.02% sodium azide
  State: Aff - Purified
  State: Liquid Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Storage: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens interferon regulatory factor 6 (IRF6), transcript variant 1
• Database Link:
  Entrez Gene 54139 MouseEntrez Gene 3664 Human
• Background: IRF6 is a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6.
• Synonyms: Interferon regulatory factor 6, IRF-6

Reference Data

• Protein Families: ES Cell Differentiation/IPS, Transcription Factors