Superoxide Dismutase 1 (SOD1) Rabbit Polyclonal Antibody

CAT#: AP22845PU-N

Superoxide Dismutase 1 (SOD1) rabbit polyclonal antibody, Purified

Product Images

Human Liver (formalin-fixed, paraffin-embedded) stained with SOD1 antibody at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.

Specifications

Product Data

• Applications: IHC, IP, WB
• Recommended Dilution: Immunohistochemistry on Frozen Sections.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Immunoprecipitation: 20 µg/ml.
  Western Blot: 0.5 - 4 µg/ml.
• Reactivities: Equine, Guinea Pig, Human, Mouse, Rat
• Host: Rabbit
• Clonality: Polyclonal
• Immunogen: Synthetic peptide surrounding amino acid 131 of Human SOD
• Specificity: This antibody recognizes Cu/Zn Superoxide Dismutase (SOD1).
• Formulation: PBS
  State: Purified
  State: Liquid purified Ig fraction
  Stabilizer: 30% Glycerol, 0.5% BSA
  Preservative: 0.01% Thimerosal
• Concentration: lot specific
• Purification: Affinity Chromatography
• Storage: Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens superoxide dismutase 1, soluble (SOD1)
• Database Link:
  Entrez Gene 20655 MouseEntrez Gene 24786 RatEntrez Gene 6647 Human
• Background: Superoxide dismutatses catalyzes the conversion of single electron reduced species of molecular oxygen to hydrogen peroxide and oxygen. Cu, Zn superoxide dismutase (SOD1) is widely distributed and comprises 90% of total SOD. Mutations in SOD1 cause a form of familial ALS. Oxidative modifications and aggregation of SOD1 has been associated with Alzheimer's and Parkinson's disease.
• Synonyms: SOD-1, CuZn-SOD, CuZnSOD, IPOA, ALS1

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Amyotrophic lateral sclerosis (ALS), Huntington's disease, Prion diseases