PPAR delta (PPARD) (430-441) Goat Polyclonal Antibody

CAT#: AP23032PU-N

PPAR delta (PPARD) (430-441) goat polyclonal antibody, Aff - Purified

Product Images

Western Blot Image: Staining (0.3ug/ml) of Jurkat lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

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  Immunohistochemistry Image: Human Breast: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Immunohistochemistry Image: Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Immunohistochemistry Image: Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/16000.
  Immunohistochemistry on Paraffin Sections: 3.75 µg/ml.
  Western Blot: 0.3 - 1 µg/ml.
• Reactivities: Bat, Bovine, Canine, Chicken, Equine, Hamster, Human, Monkey, Mouse, Porcine, Rabbit, Rat, Zebrafish
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from the C-terminus of human PPARD
• Specificity: This antibody detects PPAR-delta (C-term).
  It is expected to recognise isoform 1 (NP_006229) of PPAR delta, but not isoform 2, a shorter protein (NP_803184) with a different C-terminus.
• Formulation: Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens peroxisome proliferator activated receptor delta (PPARD), transcript variant 1
• Database Link:
  Entrez Gene 19015 MouseEntrez Gene 25682 RatEntrez Gene 5467 Human
• Background: Peroxisome proliferator-activated receptor beta/delta (PPAR beta/delta), a NR1 Thyroid Hormone-Like Receptor, is involved in the regulation of acyl-CoA synthetase 2 expression, lipid metabolism, embryo development, implantation, decidualization, and bone formation. PPAR beta/delta has been identified as a negative target of the APC gene and has been linked to colon cancer.
• Synonyms: PPAR-beta, Nuclear hormone receptor 1, NUCI, PPARD, NR1C2, PPARB

Reference Data

• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• Protein Pathways: Acute myeloid leukemia, Pathways in cancer, PPAR signaling pathway, Wnt signaling pathway