Nogo A (RTN4) (501-515) Goat Polyclonal Antibody

CAT#: AP23125PU-N

Nogo A (RTN4) (501-515) goat polyclonal antibody, Aff - Purified

Product Images

Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Testis, Human: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 2.5 µg/ml.
• Reactivities: Human, Monkey
• Host: Goat
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from an internal region of human RTN4 / Nogo (NP_065393.1; NP_997404.1)
• Specificity: This antibody detects Reticulon-4 / RTN4 (Internal).
• Formulation: Tris saline, pH 7.3 containing 0.02% sodium azide as preservative 0.5% BSA as stabilizer
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 0.5 mg/ml
• Purification: Immunoaffinity Chromatography
• Gene Name: Homo sapiens reticulon 4 (RTN4), transcript variant 1
• Database Link:
  Entrez Gene 57142 Human
• Background: This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified.
• Synonyms: Foocen, Neurite outgrowth inhibitor, NOGO, Neuroendocrine-specific protein, NSP, Reticulon-5, KIAA0886

Reference Data

• Protein Families: Transmembrane