NPY1R (C-term) Rabbit Polyclonal Antibody

CAT#: AP23327PU-N

NPY1R (C-term) rabbit polyclonal antibody, Aff - Purified

Product Images

NPY1R Polyclonal Antibody

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Western blot: At 1μg/ml with the appropriate system to detect NPY1R in cells and tissues.
  Immunohistochemistry on paraffin sections: At 1-2μg/ml to detect NPY1R in formalin fixed and paraffin embedded tissues. Boiling the sections is required.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide mapping at the C-terminal of human NPY1R
• Specificity: This antibody detects Neuropeptide Y receptor 1 (C-term).
• Formulation: 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3
  State: Aff - Purified
  State: Lyophilized Ig fraction
• Reconstitution Method: 0.2ml of distilled water will yield a concentration of 500μg/ml.
• Purification: Immunogen affinity purified
• Storage: Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens neuropeptide Y receptor Y1 (NPY1R)
• Database Link:
  Entrez Gene 18166 MouseEntrez Gene 29358 RatEntrez Gene 4886 Human
• Background: Neuropeptide Y Receptor Y1 (NPY1R) is one of the most abundant neuropeptides in the mammalian nervous system and exhibits a diverse range of important physiological activities, including effects on psychomotor activity, food intake, regulation of central endocrine secretion, and potent vasoactive effects on the cardiovascular system.. Two major subtypes of NPY receptor (Y1 and Y2) have been defined by pharmacological criteria. NPY1R and NPY2R encoding mouse type 1 and type 2 neuropeptide Y receptors, have been mapped by interspecific backcross analysis. NPY1R is required for central physiological and pharmacological NPY-induced analgesia and that its activation is both sufficient and required for the release of substance P and initiation of neurogenic inflammation.
• Synonyms: NPYR, NPYY1, Neuropeptide Y receptor 1

Reference Data

• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction