Vitamin D Binding protein (GC) Rabbit Polyclonal Antibody

CAT#: AP23593PU-N

Vitamin D Binding protein (GC) rabbit polyclonal antibody

Product Images

Human Blood Plasma: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: ELISA, IHC
• Recommended Dilution: ELISA.
  Immunohistochemistry on Paraffin Sections: 5 µg/ml.
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Native human vitamin D binding protein
• Specificity: Recognizes Vitamin D binding protein (VDBP), the major carrier protein of vitamin D that also transports components such as fatty acids and endotoxins and has an important role in the actin scavenging system. VDBP is a 52-58 kD plasma protein synthesized mainly by hepatocytes. Polymorphisms in the gene give rise to three major electrophoretic variants, Gc1, Gc1s and Gc1f that differ by amino acid substitutions as well as glycosylations. The physiological significance of these phenotypes has yet to be determined.
• Formulation: PBS containing 0.09% sodium azide as preservative
  State: Liquid purfied Ig fraction
• Concentration: lot specific
• Purification: Protein G Chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens GC, vitamin D binding protein (GC), transcript variant 1
• Database Link:
  Entrez Gene 2638 Human
• Synonyms: DBP, VDB, Group-specific component, Gc-globulin

Reference Data

• Protein Families: Secreted Protein