Suppressor of Fused (SUFU) pSer342 Rabbit Polyclonal Antibody

CAT#: AP26040PU-N

Suppressor of Fused (SUFU) pSer342 rabbit polyclonal antibody, Aff - Purified


USD 300.00

2 Weeks*

Size
    • 100 ug

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Specifications

Product Data
Applications WB
Recommended Dilution Western blot: 1:500 - 1:1000.
Reactivities Human
Host Rabbit
Clonality Polyclonal
Immunogen Peptide sequence around phosphorylation site of Serine 342 derived from Human Sufu
Specificity This antibody detects endogenous level of Sufu protein only when phosphorylated at serine 342.
Formulation Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol
State: Aff - Purified
State: Liquid Ig fraction
Concentration 1.0 mg/ml
Purification Affinity-chromatography using epitope-specific peptide
Gene Name Homo sapiens SUFU negative regulator of hedgehog signaling (SUFU), transcript variant 2
Background SUFU encodes a component of the Sonic hedgehog (SHH; MIM 600725)/Patched (PTCH; MIM 601309) signaling pathway. Mutations in genes encoding components of this pathway are deleterious for normal development and are associated with cancer-predisposing syndromes (e.g., HPE3, MIM 142945; BCNS, MIM 109400; and GCPS, MIM 175700).
Synonyms Suppressor of fused homolog
Note Molecular weight: 54 kDa
Reference Data
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Basal cell carcinoma, Hedgehog signaling pathway, Pathways in cancer

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.