Mmp2 Rabbit Polyclonal Antibody
Other products for "Mmp2"
Specifications
Product Data | |
Applications | IP, WB |
Recommended Dilution | Western blot (0.5-4 µg/ml). Immunoprecipitation (4-8 µg/ml). |
Reactivities | Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | E. coli-expressed active rat 72-kDa type IV collagenase |
Specificity | This antibody detects MMP-2. It has no cross-reactivity with other MMP family members. |
Formulation | Phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal State: Aff - Purified State: Liquid Ig fraction |
Concentration | 0.5 mg/ml |
Purification | Affinity chromatography |
Gene Name | Rattus norvegicus matrix metallopeptidase 2 (Mmp2) |
Database Link | |
Background | The mammalian Matrix metalloproteinases (MMPs) degrade extracellular matrix in physiological and pathological processes. After cleavage of a single peptide domain of about 20 amino acids, the MMPs are secreted in latent forms. Upon activation, the N-terminal propeptide domain is cleaved to generate the active forms of MMP. MMP-2 (72 kDa type IV collagenase, Gelatinase-A) contains the basic structure of propeptide, catalytic, and hemopexin domains. It is an important proteinase in tissue remodeling. |
Synonyms | MMP2, CLG4A, 72 kDa gelatinase, Matrix metalloproteinase-2, Gelatinase A, TBE-1 |
Reference Data |
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