c-Myb (MYB) (241-254) Goat Polyclonal Antibody

CAT#: AP31017PU-N

c-Myb (MYB) (241-254) goat polyclonal antibody, Aff - Purified

Product Images

Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)

• 

  Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 3.75 - 7.5 µg/ml.
• Reactivities: Bat, Canine, Equine, Human, Monkey, Porcine, Rabbit
• Host: Goat
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from positions 241-254 of human MYB (NP_001123645.1)
• Specificity: This antibody reacts to V-myb Myeloblastosis Viral Oncogene Homolog (MYB) at aa241-254.
  It is expected to recognize all reported isofoms (NP_001123645.1; NP_005366.2; NP_001123644.1; NP_001155128.1; NP_001155129.1; NP_001155130.1; NP_001155131.1; NP_001155132.1).
• Formulation: Tris saline buffer, pH 7.3 containing 0.5% BSA as stabilizer and 0.02% sodium azide as preservative
  State: Aff - Purified
  State: Liquid purfied Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Upon receipt, store undiluted (in aliquots) at -20°C.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens MYB proto-oncogene, transcription factor (MYB), transcript variant 3
• Database Link:
  Entrez Gene 4602 Human
• Background: MYB / c-Myb is a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants.
• Synonyms: c-Myb

Reference Data

• Protein Families: Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Transcription Factors