Cytokeratin 19 (KRT19) Rabbit Polyclonal Antibody

CAT#: AP31607PU-N

Cytokeratin 19 (KRT19) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of extracts from LOVO cells, using Keratin 19 Antibody. The lane on the right is treated with the synthesized peptide.

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  Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/10000.
  Immunohistochemistry on Paraffin Sections: 1/200.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human, Mouse, Rat
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide
• Specificity: This antibody detects endogenous levels of total Keratin 19 protein.
• Formulation: PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride and 50% Glycerol
  State: Purified
  State: Liquid purified Ig fraction
  Preservative: 0.02% Sodium Azide
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody (in aliquots) at -20°C.
  Avoid freeze-thaw cycles.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens keratin 19 (KRT19)
• Database Link:
  Entrez Gene 16669 MouseEntrez Gene 360626 RatEntrez Gene 3880 Human
• Background: Cytokeratin 19 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. KRT19 is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.
• Synonyms: Cytokeratin-19, Keratin-19, KRT19, CK19, K19