TLR9 (26-300) Rabbit Polyclonal Antibody

CAT#: AP31723PU-N

TLR9 (26-300) rabbit polyclonal antibody, Aff - Purified

Product Images

Sample (30 ug of whole cell lysate) A: THP-1. 7.5% SDS PAGE. TLR9 antibody diluted at 1/1000.

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  Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: Immunohistochemistry on Paraffin Sections: 5 µg/ml.
  Western Blot: 1/500 - 1/3000.
• Reactivities: Human
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Recombinant protein fragment containing a sequence corresponding to a region within amino acids 26 and 300 of Human CD289(TLR9)
• Specificity: This antibody detects Toll-like Receptor 9 (TLR9) at aa 26-300.
• Formulation: 0.1 M Tris-glycine, pH 7, 10% Glycerol and 0.01% Thimerosal
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: 0.71 mg/ml
• Purification: Immunoaffinity Chromatography
• Gene Name: Homo sapiens toll like receptor 9 (TLR9)
• Database Link:
  Entrez Gene 54106 Human
• Background: TLR9 is a member of the Toll like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The gene encoding this protein is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X.
• Synonyms: Toll-like receptor 9, UNQ5798/PRO19605

Reference Data

• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Toll-like receptor signaling pathway