Galectin 8 (LGALS8) Rabbit Polyclonal Antibody

CAT#: AP31763PU-N

Galectin 8 (LGALS8) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of extracts from NIH-3T3 cells, using LEG8 Antibody. The lane on the right is treated with the synthesized peptide.

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  Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE)

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  Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

Specifications

Product Data

• Applications: ELISA, IHC, WB
• Recommended Dilution: ELISA: 1/20000.
  Immunohistochemistry on Paraffin Sections: 1/200.
  Western Blot: 1/500 - 1/1000.
• Reactivities: Human, Mouse
• Host: Rabbit
• Isotype: IgG
• Clonality: Polyclonal
• Immunogen: Synthetic peptide from Human LEG8.
  Epitope: Internal (aa 61-110).
• Specificity: This antibody detects endogenous levels of total LEG8 protein.
• Formulation: PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02% Sodium Azide and 50% Glycerol
  State: Aff - Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Immunoaffinity Chromatography
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: Homo sapiens galectin 8 (LGALS8), transcript variant 1
• Database Link:
  Entrez Gene 56048 MouseEntrez Gene 3964 Human
• Background: Several proteins have been identified as specific markers of prostate cancer, and they may be useful as diagnostic indicators. PSA, prostate specific antigen, is the classical indicator for transformed prostate tissue; however, in addition to being upregulated in prostate cancer, PSA is also upregulated in non-malignant conditions, such as benign prostatic hyperplasia prostate. Galectin-8, also known as prostate-specific membrane antigen (PCTA-1), is an additional prostate-specific antigen that is overexpressed only in malignant tumors and therefore is a more specific identifier of malignancies. It is a member of the galectin gene family which mediates both cell-cell and cellmatrix interactions in a manner similar to the selectin subgroup of C-type lectins.
• Synonyms: LGALS8, Galectin8, Gal-8, Prostate carcinoma tumor antigen 1, PCTA-1, Po66 carbohydrate-binding protein, Po66-CBP