15 Lipoxygenase 2 (ALOX15B) (C-term) Rabbit Polyclonal Antibody

CAT#: AP50153PU-N

15 Lipoxygenase 2 (ALOX15B) (C-term) rabbit polyclonal antibody, Purified

Product Images

Western blot analysis of ALOX15B Antibody (C-term) in CEM cell line lysates (35ug/lane). ALOX15B (arrow) was detected using the purified Pab.

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  Formalin-fixed and paraffin-embedded human skin tissue reacted with PSMD13 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western blotting: 1/50 - 1/100.
  Immunohistochemistry: 1/50 - 1/100.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 605~634 amino acids from the C-terminal region of human ALOX15B
• Specificity: this antibody reacts to ALOX15B.
• Formulation: PBS containing 0.09% (W/V) sodium azide as preservative
  State: Purified
  State: Liquid purified Ig fraction
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Conjugation: Unconjugated
• Storage: Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.
• Stability: Shelf life: one year from despatch.
• Gene Name: arachidonate 15-lipoxygenase, type B
• Database Link:
  Entrez Gene 247 Human
  UniProt ID O15296
• Background: ALOX15B encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17.
• Synonyms: 15-LOX-2, Arachidonate 15-lipoxygenase type II
• Note: Molecular Weight: 75885 Da

Reference Data

• Protein Families: Druggable Genome
• Protein Pathways: Arachidonic acid metabolism, Metabolic pathways