TCP1 delta (CCT4) (N-term) Rabbit Polyclonal Antibody

CAT#: AP50829PU-N

TCP1 delta (CCT4) (N-term) rabbit polyclonal antibody, Aff - Purified

Product Images

CCT4 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the CCT4 antibody detected the CCT4 protein (arrow).

Specifications

Product Data

• Applications: WB
• Recommended Dilution: ELISA: 1/1000.
  Western blot: 1/100 - 1/500.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 3-32 amino acids from the N-terminal region of human CCT4
• Specificity: This antibody reacts to CCT4.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 57924 Da
• Gene Name: Homo sapiens chaperonin containing TCP1 subunit 4 (CCT4), transcript variant 1
• Database Link:
  Entrez Gene 10575 Human
• Background: The chaperonin containing TCP1 (MIM 186980) complex (CCT), also called the TCP1 ring complex, consists of 2 back-to-back rings, each containing 8 unique but homologous subunits, such as CCT4. CCT assists the folding of newly translated polypeptide substrates through multiple rounds of ATP-driven release and rebinding of partially folded intermediate forms. Substrates of CCT include the cytoskeletal proteins actin (see MIM 102560) and tubulin (see MIM 191130), as well as alpha-transducin (MIM 139330) (Won et al., 1998 [PubMed 9819444]).
• Synonyms: CCTD, CCT delta, SRB

Reference Data

• Protein Families: Druggable Genome