Properdin (CFP) (Center) Rabbit Polyclonal Antibody

CAT#: AP50880PU-N

Properdin (CFP) (Center) rabbit polyclonal antibody, Aff - Purified

Product Images

Western blot analysis of CFP Antibody (Center) in CEM cell line lysates (35ug/lane). CFP (arrow) was detected using the purified Pab.

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  CFP Antibody (Center) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

Specifications

Product Data

• Applications: IHC, WB
• Recommended Dilution: ELISA: 1/1000.
  Western Blot: 1/100 - 1/500.
  Flow Cytometry: 1/10 - 1/50.
• Reactivities: Human
• Host: Rabbit
• Isotype: Ig
• Clonality: Polyclonal
• Immunogen: KLH conjugated synthetic peptide between 203~233 amino acids from the Central region of human CFP
• Specificity: This antibody reaccts to CFP.
• Formulation: PBS
  State: Aff - Purified
  State: Liquid purified Ig fraction
  Preservative: 0.09% (W/V) sodium azide
• Concentration: lot specific
• Purification: Affinity chromatography on Protein A
• Storage:

  Store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
  Avoid repeated freezing and thawing.

• Stability: Shelf life: one year from despatch.

• Predicted Protein Size: 51276 Da
• Gene Name: Homo sapiens complement factor properdin (CFP), transcript variant 2
• Database Link:
  Entrez Gene 5199 Human
• Background: This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections.
• Synonyms: CFP, PFC, Complement factor P

Reference Data

• Protein Families: Secreted Protein